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Leishmania

All you need to know about Leishmania, Leishmaniasis, its Drugs, Diagnosis and Treatment

Why this website?

Collecting scattered information hence, saving
​time, energy & resources

What is Leishmaniasis?

One of the major health problems in the tropical and sub-tropical regions of the world is Leishmaniasis. Leishmaniasis dates to 2,500 B.C. with several primitive descriptions found in ancient writings and manuscripts also from recent molecular findings of ancient archaeological material.

Causal Organism

Know more about Leishmania here.

Vector

Know more about Phlebotome here.

Types of Leishmaniasis?

Majorly there are 3 types of this infection:

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Visceral Leishmaniasis

Cutaneous Leishmaniasis

Mucocutaneous Leishmaniasis

Types of Leishmaniasis?

Majorly there are 3 types of this infection:

​

Visceral Leishmaniasis

Cutaneous Leishmaniasis

Mucocutaneous Leishmaniasis

Viscreal Leishmaniasis

Visceral Leishmaniasis is also known as Kala-azar (Indian sub-continent).

Cutaneous Leishmaniasis

 Dermal infection caused mostly by L. major,

L. tropica, and L. infantum.

Mucoutaneous Leishmaniasis

 Also known as 'espundia'. It happens a long time after the onset of CL.

Geographical distribution of Leishmaniasis infection

With Leishmaniasis being the ninth largest disease burden amongst infectious diseases, it covers almost all the globe with majority of cases prevailing in developing and underdeveloped countries.

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Geographical distribution of Leishmaniasis infection

With Leishmaniasis being the ninth largest disease burden amongst infectious diseases, it covers almost all the globe with majority of cases prevailing in developing and underdeveloped countries.

Geographical distribution of Leishmaniasis infection cases across globe (2004-2009)

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Diagnosis

The analysis of leishmaniasis is affirmed by the finding of the etiological specialist or its antigen or particle in the example got from the injury.

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Parasitological diagnosis

Discovery of Leishmania DNA

Immunological test-based diagnosis

Serological and Molecular diagnosis

Treatment and Drugs

Leishmanial infections are primarily controlled by chemotherapeutic measures (very limited) that comprises of only five drugs:

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Pentavalent antimonials

Pentamidine

Miltefosine

Paromomycin

Amphotericin B

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